The GABBR2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GABBR2. This antibody recognizes Human, Mouse, and Rat antigen. The GABBR2 Polyclonal Antibody has been validated for the following applications: Western Blot.
Description
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence